4 edition of Pharmacological Aspects of Molecular Recognition found in the catalog.
November 30, 2005
by Novinka Books
Written in English
|The Physical Object|
|Number of Pages||214|
This is an updated, expanded new edition of Dr. Ruth Levine's renowned Pharmacology: Drug Actions and Reactions. It covers basic pharmacological principles and the general concepts of chemical-biological interactions and now includes important new material on molecular biology, updated clinical information, and added coverage of the newer drugs.4/5(3). Molecular pharmacology seeks to determine how drugs work on a molecular basis. One of the most important aspects of molecular pharmacology is understanding how drugs work on a molecular basis. For a patient who takes antibiotics for an infection, the molecular explanation for the efficacy of the drugs might not seem terribly important, as long.
Title:Molecular Aspects of Resistance to Biological and Non-Biological Drugs and Strategies to Overcome Resistance in Colorectal Cancer VOLUME: 21 ISSUE: 14 Author(s):T. Troiani, E. Martinelli, S. Napolitano, F. Morgillo, G. Belli, L. Cioffi and F. Ciardiello Affiliation:Dipartimento Medico- Chirurgico di Internistica Clinica e Sperimentale “F. Magrassi e A. Lanzara”, Seconda Università. Heterotrimeric G proteins, composed of Gα and Gβγ subunits, transduce extracellular signals via G-protein-coupled receptors to modulate many important intracellular responses. The Gβγ subunits hold a central position in this signaling system and have been implicated in multiple aspects of physiology and the pathophysiology of disease. The Gβ subunit belongs to a large family of WD
Atomic Interactions of Ligands with AChBP. All four pyridine rings of IMI, THIA, NIC (), and EPI virtually overlap with the pyridine nitrogen in a common position (Fig. 3).The three AChBP-ligand x-ray structures with the higher resolution (IMI, THIA, and NIC) have an associated water in the same position near Ile Abstract. In this chapter some background material concerning molecular chirality and enantiomerism is presented. First some basic chemical-molecular aspects of chirality are reviewed, after which certain relevant terminology whose use in the literature has been problematic is discussed.
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: Molecular Recognition: Pharmacological Aspects () by Dukhovich, F. S.; Darkhovskii, M. B.; Gorbatova, E. N.; Kurochkin, V. and a great Price Range: $ - $ ISBN: OCLC Number: Description: x, pages: illustrations ; 26 cm: Contents: Ch.
Molecular recognition in the ligand-receptor system: introduction to the problem --Ch. that participate in drug-receptor complex formation and energy of intermolecular interactions --Ch.
dynamics and kinetics of drug-receptor complex formation --Ch. Isomerization of Receptors --Drug Interactions with Specific and Non-Specific Receptors at a Distance and under a Contact --Distant Recognition and Molecular Electrostatic Potential --Quantitative Aspects of Ligands Binding to Specific Receptors.
Example of Muscarinic Acetylcholine Receptor' Ligands. About this book With its exploration of the scientific and technological characteristics of systems exploiting molecular recognition between synthetic materials, such as polymers and nanoparticles, and biological entities, this is a truly multidisciplinary book bridging chemistry, life sciences, pharmacology.
Molecular Pharmacology: The Model of Action of Biologically Active Compounds, Volume 1 discusses the mode of action of bioactive compounds on a molecular level. This book reviews the processes that control the uptake of drugs, their diffusion through tissues, as Book Edition: 1. Pharmacological Aspects of Molecular Recognition.
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Pharmacology is a branch of medicine and pharmaceutical sciences which is concerned with the study of drug or medication action, where a drug can be broadly or narrowly defined as any man-made, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word pharmacon is used as a term to.
Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy, Volume Seven, describes the fundamental aspects of efflux pumps of the ATP-binding cassette superfamily in cancer resistance pathways, along with strategies to target and improve chemotherapy.
Pharmacology, branch of medicine that deals with the interaction of drugs with the systems and processes of living animals, in particular, the mechanisms of drug action as well as the therapeutic and other uses of the drug.
The first Western pharmacological treatise, a listing of herbal plants used in classical medicine, was made in the 1st century ad by the Greek physician Dioscorides.
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Print Book & E-Book. ISBNFigure 1. Dinoponera quadriceps (Quinet, Y.P. ) Like all Aculeata hymenopterans (Chrysidoidea, Apoidea, Vespoidea), Dinoponera ants have a sting apparatus that is located in the last portion of the gaster, and is formed by the sting itself (derived from the ovipositor of more basal hymenopteran groups) along with two associated glands: the Dufour’s gland and the venom gland [4,13].
Special Issue in International Journal of Molecular Sciences: Modulation of Oxidative Stress: Molecular and Pharmacological Aspects Special Issue in Antioxidants: Modulators of Oxidative Stress: Chemical and Pharmacological Aspects Special Issue in Molecules: Chemistry, Biology and Pharmacology of Modulators of Oxidative Stress.
GABA (gamma-aminobutyric acid) is the main neurotransmitter regulating sleep. The majority of drugs presently in use for the treatment of sleep disorders act by enhancing GABAergic neuronal inhibition. Chemistry and Molecular Aspects of Drug Design and Action book.
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View abstract. With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and s: 5.
The basic aspects of ligand-protein interaction may be summarized under the term 'molecular recognition' and concern the specificity as well as stability of ligand binding.
Molecular recognition is thus a central topic in the development of active substances, since stability and specificity determine whether a substance can be used as a drug. Because of this design constraint, a synthesis of SK&Fwhich is amenable to large-scale production has become a significant challenge.
In order to synthesize the multi-kilogram quantities of SK&F that would be required for clinical development, major modifications are needed in some key aspects of the chemistry. Biochemical Pharmacology40 (1), DOI: /(90)J. WALTHO, D. WILLIAMS. ChemInform Abstract: Aspects of Molecular Recognition: Solvent Exclusion and Dimerization of the Antibiotic Ristocetin When Bound to a Model Bacterial Cell-Wall Precursor.
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Understanding molecular recognition by G protein βγ subunits on the path to pharmacological targeting. Lin Y(1), Smrcka AV. Author information: (1)Department of Pharmacology, University of Rochester School of Medicine and Dentistry, Rochester, NYUSA.Basic pharmacological research on all types of biologicals, botanicals, chemicals, phytochemicals, with the aim of investigating molecular recognition processes in the action of biologically active products.
Molecular biological studies of macromolecular targets that lead to an improved understanding of molecular recognition.This issue of Chemical Reviews should be of interest to both the novice and the specialist in molecular recognition, because of the breadth of topics and approaches covered in the articles.
The range of phenomena under the rubric of molecular recognition is so wide that no researcher active in one part of this field can stay current on developments in the many other parts.